Intrauterine insemination has been proposed for a long time and its place took benefits from the knowledge in IVF: sperm preparation and ovarian stimulation. Initially the first line therapy for male factor, cervical factor and unexplained infertility, it became also proposed for endometriosis, ovarian dysfunction, and even for tubal factor. About 44,000 to 45,000 cycles are done in France each year, and pregnancy rate per cycle are various, between 10 to 15-20%. Intrauterine insemination is now the first ART's therapy. This review points the prerequisite evaluations, and the efficiency depending on predictive factors.
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